About 1 result found for searched term "ICCB-19 hydrochloride" (0.575 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10731 | ICCB-19 hydrochloride | Autophagy |
| ICCB-19 hydrochloride is a TRADD (TNFRSF1A associated via death domain) inhibitor. ICCB-19 hydrochloride binds to the N-terminal domain of TRADD (TRADD-N), breaking its binding to TRADD-C and TRAF2. ICCB-19 hydrochloride is an indirect inhibitor of RIPK1 kinase activity. ICCB-19 hydrochloride effectively induces autophagy and degradation of long-lived proteins. | ||
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